JNJ-38877605

Catalog No.: A10493
c-Met inhibitor
c-Met inhibitor JNJ-38877605 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways.
Grouped product items
Product Name Price Stock Qty
JNJ-38877605 5mg
Special Price $48.00 Regular Price $60.00
In stock
JNJ-38877605 10mg
Special Price $80.00 Regular Price $100.00
In stock
JNJ-38877605 50mg
Special Price $240.00 Regular Price $300.00
In stock
JNJ-38877605 100mg
Special Price $400.00 Regular Price $500.00
In stock
JNJ-38877605 10mM * 1mL in DMSO
Special Price $83.20 Regular Price $104.00
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Biological Activity
Discription c-Met inhibitor JNJ-38877605 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways.
Product Information
Catalog Num A10493
Formula C19H13F2N7
Molecular Weight 377.4
CAS Number 943540-75-8
SMILES CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 33 mg/mL (87.45 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.5 mL 132.49 mL 264.97 mL
0.5 mM 5.3 mL 26.5 mL 52.99 mL
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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