JNJ-38877605

Catalog No.: A10493

c-Met inhibitor

JNJ-38877605

JNJ-38877605 Chemical Structure

CAS NO. 943540-75-8

c-Met inhibitor JNJ-38877605 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $60.00

Special Price $54.00

10 mg

Regular Price: $100.00

Special Price $90.00

50 mg

Regular Price: $300.00

Special Price $270.00

100 mg

Regular Price: $500.00

Special Price $450.00

10mM * 1mL in DMSO

Regular Price: $104.00

Special Price $93.60

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

c-Met inhibitor JNJ-38877605 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways.
In vitro (25°C) DMSO 37 mg/mL (98.05 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.5 mL 132.49 mL 264.97 mL
0.5 mM 5.3 mL 26.5 mL 52.99 mL
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL

*The above data is based on the productmolecular weight 377.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10493
Actions Inhibitor
M. Wt 377.4
Formula C19H13F2N7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 943540-75-8
Synonyms JNJ38877605
SMILES CN1C=C(C=N1)C2=NN3C(=NN=C3C(C4=CC5=C(C=C4)N=CC=C5)(F)F)C=C2

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