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KU-60019

Catalog No.: A10507
ATM Inhibitor
Adooq's KU-60019 has been cited by 6 publications
KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.
KU-60019
Grouped product items
Product Name Price Stock Qty
KU-60019 10mg
Special Price $72.00 Regular Price $90.00
In stock
KU-60019 50mg
Special Price $240.00 Regular Price $300.00
In stock
KU-60019 100mg
Special Price $400.00 Regular Price $500.00
In stock
KU-60019 10mM * 1mL in DMSO
Special Price $86.40 Regular Price $108.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's KU-60019 has been cited by 6 publications
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Yuri Tozaki, .et al. , Cancers (Basel), 2023, Jan 25;15(3):735 PMID: 36765693
  • Fu-Xing Gong, .et al. , Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458
  • Hegedus C, .et al. , Cancers (Basel), 2019, Dec 18;12(1) PMID: 31861350
  • Masaya Igase, .et al. , Mol Ther Oncolytics, 2019, vol 15 PMID: 31650025
  • CHENGHUA LOU, .et al. , Oncol Lett, 2016, Jul; 12(1): 295-300 PMID: 27347141
    • Biological Activity
    Discription KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.
    Targets
    Target Value
    Product Information
    Catalog Num A10507
    Formula C30H33N3O5S
    Molecular Weight 547.7
    CAS Number 925701-49-1, 925701-46-8
    SMILES C[C@@H]1CN(C[C@@H](O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro DMSO Warmed: 18 mg/mL (32.86 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.26 mL 91.29 mL 182.58 mL
    0.5 mM 3.65 mL 18.26 mL 36.52 mL
    1 mM 1.83 mL 9.13 mL 18.26 mL
    5 mM 0.37 mL 1.83 mL 3.65 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    PI3K/Akt/mTOR > ATM/ATR
    DNA Damage > ATM/ATR
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