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KU-60019

Catalog No.: A10507
ATM Inhibitor
Adooq's KU-60019 has been cited by 7 publications
KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.
KU-60019
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
5mg
$65.00
In stock
10mg
$85.00
In stock
25mg
$185.00
In stock
50mg
$295.00
In stock
100mg
$495.00
In stock
10mM * 1mL in DMSO
$80.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's KU-60019 has been cited by 7 publications
  • Erika Nakatsuka, .et al. , Transl Oncol, 2024, Sep 12:50:102119 PMID: 39270525
  • Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418
  • Yuri Tozaki, .et al. , Cancers (Basel), 2023, Jan 25;15(3):735 PMID: 36765693
  • Fu-Xing Gong, .et al. , Nucleic Acids Res, 2021, Sep 20;49(16):9342-9352 PMID: 34403458
  • Hegedus C, .et al. , Cancers (Basel), 2019, Dec 18;12(1) PMID: 31861350
  • Masaya Igase, .et al. , Mol Ther Oncolytics, 2019, vol 15 PMID: 31650025
  • CHENGHUA LOU, .et al. , Oncol Lett, 2016, Jul; 12(1): 295-300 PMID: 27347141
    • Biological Activity
    Discription KU-60019 is a potent and specific ATM inhibitor with IC50 of 6.3 nM.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10507
    Formula C30H33N3O5S
    Molecular Weight 547.7
    CAS Number 925701-49-1, 925701-46-8
    SMILES C[C@@H]1CN(C[C@@H](O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro DMSO Warmed: 18 mg/mL (32.86 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.26 mL 91.29 mL 182.58 mL
    0.5 mM 3.65 mL 18.26 mL 36.52 mL
    1 mM 1.83 mL 9.13 mL 18.26 mL
    5 mM 0.37 mL 1.83 mL 3.65 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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    • Calculator Reset
    PI3K/Akt/mTOR > ATM/ATR
    DNA Damage > ATM/ATR
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