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$0.00 - Hiroki Murano, .et al. A purine-type heat shock protein 90 inhibitor promotes the heat shock response in Arabidopsis, Plant Biotechnol Rep, 2017, 11:107-113
Biological Activity
KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
Targets
| HSP90 | ||||
| 3.8 nM |
| In vitro (25°C) | DMSO | 114 mg/mL (198.37 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (5.22 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.4 mL | 87.01 mL | 174.02 mL |
| 0.5 mM | 3.48 mL | 17.4 mL | 34.8 mL |
| 1 mM | 1.74 mL | 8.7 mL | 17.4 mL |
| 5 mM | 0.35 mL | 1.74 mL | 3.48 mL |
*The above data is based on the productmolecular weight 574.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11195 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 819812-04-9 |
| Formula | C30H42N2O9 |
| M. Wt | 574.66 |
| Purity | >98% |
| Synonyms | KW2478 |
| SMILES | CCC1=C(C=C(C(=C1CC(=O)N(CCOC)CCOC)C(=O)C2=CC(=C(C=C2)OCCN3CCOCC3)OC)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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