KW-2478

Catalog No.: A11195
HSP90 inhibitor

KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

Grouped product items
Product Name Stock
KW-2478 5mg
KW-2478 10mg
KW-2478 50mg
KW-2478 100mg
KW-2478 10mM * 1mL in DMSO
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's KW-2478 has been cited by 1 publications
  • Hiroki Murano, .et al. , Plant Biotechnol Rep, 2017, 11:107-113
  • Biological Activity
    Discription

    KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

    Targets
    Target Value
    Product Information
    Catalog Num A11195
    Formula C30H42N2O9
    Molecular Weight 574.66
    CAS Number 819812-04-9
    SMILES CCC1=C(C=C(C(=C1CC(=O)N(CCOC)CCOC)C(=O)C2=CC(=C(C=C2)OCCN3CCOCC3)OC)O)O
    Synonyms KW2478
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 114 mg/mL (198.37 mM)
    Water Insoluble
    Ethanol 3 mg/mL (5.22 mM)
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.4 mL 87.01 mL 174.02 mL
    0.5 mM 3.48 mL 17.4 mL 34.8 mL
    1 mM 1.74 mL 8.7 mL 17.4 mL
    5 mM 0.35 mL 1.74 mL 3.48 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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