Lapatinib Ditosylate

Catalog No.: A10514
HER2 inhibitor
Lapatinib is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway.
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Product Name Price Stock Qty
Lapatinib Ditosylate 25mg
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Lapatinib Ditosylate 50mg
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Lapatinib Ditosylate 100mg
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Lapatinib Ditosylate 200mg
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Lapatinib Ditosylate 10mM * 1mL in DMSO
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Lapatinib is a dual tyrosine kinase inhibitor which interrupts the HER2 growth receptor pathway.
Target Value
Product Information
Catalog Num A10514
Formula C43H42ClFN4O10S3
Molecular Weight 925.46
CAS Number 388082-77-7
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 93 mg/mL (100.49 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.81 mL 54.03 mL 108.05 mL
0.5 mM 2.16 mL 10.81 mL 21.61 mL
1 mM 1.08 mL 5.4 mL 10.81 mL
5 mM 0.22 mL 1.08 mL 2.16 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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