Leflunomide

Catalog No.: A10521

Dehydrogenase inhibitor

Leflunomide

Leflunomide Chemical Structure

CAS NO. 75706-12-6

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain.

Availability: In stock

Package Price Qty
100 mg
$50.00
500 mg
$150.00
10mM * 1mL in DMSO
$55.00
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Biological Activity

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain.
Targets
Dihydroorotate dehydrogenase
In vitro DMSO 54 mg/mL (199.84 mM
Water <1 mg/mL (<1 mM)
Ethanol 54 mg/mL (199.84 mM
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.01 mL 185.05 mL 370.1 mL
0.5 mM 7.4 mL 37.01 mL 74.02 mL
1 mM 3.7 mL 18.5 mL 37.01 mL
5 mM 0.74 mL 3.7 mL 7.4 mL

*The above data is based on the productmolecular weight 270.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10521
Actions Inhibitor
M. Wt 270.2
Formula C12H9F3N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 75706-12-6
Synonyms Arava
SMILES CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F

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