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Publications citing Adooq Products
LY2886721 Citations (1)
- Naomi Ito,et al. miR坼15b mediates oxaliplatin坼induced chronic neuropathic pain through BACE1 down坼regulation, Br J Pharmacol, 2017, Mar; 174(5): 386-395 28012171
Chemical Information
| Catalog Num | A10543 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 390.4 |
| Formula | C18H16F2N4O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1262036-50-9 |
| Synonyms | LY-2886721 |
| SMILES code | C1[[email protected]]2CSC(=N[[email protected]]2(CO1)C3=C(C=CC(=C3)NC(=O)C4=NC=C(C=C4)F)F)N |
| Chemical Name | N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide |
Description |
LY2886721 is a novel potent agent that is used to treat Alzheimer's Disease in preclinical experiments. | ||||||||||
Targets |
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| Solubility (25°C)* | In vitro | DMSO | 9 mg/mL (23.05 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.61 mL | 128.07 mL | 256.15mL |
| 0.5 mM | 5.12 mL | 25.61 mL | 51.23 mL |
| 1 mM | 2.56 mL | 12.81 mL | 25.61 mL |
| 5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
*The above data is based on the productmolecular weight 390.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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