Signaling Pathway
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| Discription | LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor. | ||
|---|---|---|---|
| Targets |
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| Catalog Num | A10549 |
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| Formula | C32H31F2N3O2.3HCl |
| Molecular Weight | 637 |
| CAS Number | 167465-36-3 |
| SMILES | C1CN(CCN1C[C@H](COC2=CC=CC3=C2C=CC=N3)O)C4C5=CC=CC=C5[C@H]6[C@H](C6(F)F)C7=CC=CC=C47.Cl.Cl.Cl |
| Synonyms | LY-335979, Zosuquidar trihydrochloride,RS-33295-198 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 93 mg/mL (145.99 mM) | |
| Water | 21 mg/mL (32.96 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.7 mL | 78.49 mL | 156.99 mL |
| 0.5 mM | 3.14 mL | 15.7 mL | 31.4 mL |
| 1 mM | 1.57 mL | 7.85 mL | 15.7 mL |
| 5 mM | 0.31 mL | 1.57 mL | 3.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
