LY335979 (Zosuquidar 3HCl)

Catalog No.: A10549

P-gp modulator

LY335979 (Zosuquidar 3HCl)

LY335979 (Zosuquidar 3HCl) Chemical Structure

CAS NO. 167465-36-3

LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor.

Availability: In stock

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5 mg

Regular Price: $50.00

Special Price $40.00

10 mg

Regular Price: $80.00

Special Price $64.00

50 mg

Regular Price: $240.00

Special Price $192.00

100 mg

Regular Price: $400.00

Special Price $320.00

10mM * 1mL in DMSO

Regular Price: $123.00

Special Price $98.40

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Biological Activity

LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor.
Targets
P-gp (Cell-free assay)
60 nM(Ki)
In vitro (25°C) DMSO 93 mg/mL (145.99 mM)
Water 21 mg/mL (32.96 mM)
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.7 mL 78.49 mL 156.99 mL
0.5 mM 3.14 mL 15.7 mL 31.4 mL
1 mM 1.57 mL 7.85 mL 15.7 mL
5 mM 0.31 mL 1.57 mL 3.14 mL

*The above data is based on the productmolecular weight 637.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10549
Actions Modulator
CAS No. 167465-36-3
Formula C32H31F2N3O2.3HCl
M. Wt 637.0
Purity >98%
Synonyms LY-335979, Zosuquidar trihydrochloride,RS-33295-198
SMILES C1CN(CCN1C[[email protected]](COC2=CC=CC3=C2C=CC=N3)O)C4C5=CC=CC=C5[[email protected]]6[[email protected]](C6(F)F)C7=CC=CC=C47.Cl.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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