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Nicotinic receptor agonist

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Catalog No. A11545

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Metanicotine 10mg A11545-10
Metanicotine 25mg A11545-25
Metanicotine 50mg A11545-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Metanicotine is a neuronal nicotinic receptor agonist, showing high selectivity for the ??4??2 subtype (Ki=26 nM); > 1,000 fold selectivity than ??7 receptors(Ki= 36000 nM).


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Chemical Information

Catalog Num A11545
Actions Agonist
M. Wt 162.23
Formula C10H14N2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 15585-43-0
Synonyms Rivanicline, RJR 2403
Chemical Name (E)-N-methyl-4-pyridin-3-ylbut-3-en-1-amine

Biological Activity

Metanicotine is a neuronal nicotinic receptor agonist, showing high selectivity for the ??4??2 subtype (Ki=26 nM); > 1,000 fold selectivity than ??7 receptors(Ki= 36000 nM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 61.64 mL 308.2 mL 616.41mL
0.5 mM 12.33 mL 61.64 mL 123.28 mL
1 mM 6.16 mL 30.82 mL 61.64 mL
5 mM 1.23 mL 6.16 mL 12.33 mL

*The above data is based on the productmolecular weight 162.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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