Signaling Pathway
Important Notice: For research use only. We do not sell to patients.
| Discription | Metolazone and the other thiazide diuretics inhibit the function of the sodium-chloride symporter and prevent sodium and chloride, water as well, from leaving the lumen to enter the tubule cell. |
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| Catalog Num | A10584 |
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| Formula | C16H16ClN3O3S |
| Molecular Weight | 365.8 |
| CAS Number | 17560-51-9 |
| SMILES | CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl |
| Synonyms | Zaroxolyn, Mykrox, Zytanix |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 68 mg/mL (185.87 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (19.13 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.34 mL | 136.69 mL | 273.37 mL |
| 0.5 mM | 5.47 mL | 27.34 mL | 54.67 mL |
| 1 mM | 2.73 mL | 13.67 mL | 27.34 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.47 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
