MK-8033

Catalog No.: A11489

c-Met inhibitor

MK-8033

MK-8033 Chemical Structure

CAS NO. 1001917-37-8

MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.

Availability: In stock

Package Price Qty
5 mg
$300.00
10 mg
$550.00
25 mg
$1,200.00
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Biological Activity

MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.04 mL 212.08 mL
0.5 mM 4.24 mL 21.21 mL 42.42 mL
1 mM 2.12 mL 10.6 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11489
Actions Inhibitor
CAS No. 1001917-37-8
Formula C25H21N5O3S
M. Wt 471.53
Solubility DMSO
Purity >98%
Synonyms MK 8033, MK8033
SMILES CN1C=C(C=N1)C2=CN=C3C=CC4=C(C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)C(=O)C3=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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