Catalog No.: A11403
SCD inhibitor
MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
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MK-8245 5mg
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MK-8245 10mg
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MK-8245 50mg
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MK-8245 100mg
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MK-8245 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's MK-8245 has been cited by 1 publications
  • Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467
  • Biological Activity
    Discription MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
    Target Value
    Product Information
    Catalog Num A11403
    Formula C17H16BrFN6O4
    Molecular Weight 467.3
    CAS Number 1030612-90-8, 1030612-87-3
    Synonyms MK8245

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 89 mg/mL (190.47 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% CMC+0.5% Tween-80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.4 mL 107 mL 214 mL
    0.5 mM 4.28 mL 21.4 mL 42.8 mL
    1 mM 2.14 mL 10.7 mL 21.4 mL
    5 mM 0.43 mL 2.14 mL 4.28 mL
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