Catalog No.: A11403

SCD inhibitor


MK-8245 Chemical Structure

CAS NO. 1030612-90-8, 1030612-87-3

MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.

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5 mg

Regular Price: $110.00

Special Price $88.00

10 mg

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Special Price $136.00

50 mg

Regular Price: $485.00

Special Price $388.00

100 mg

Regular Price: $675.00

Special Price $540.00

10mM * 1mL in DMSO

Regular Price: $80.00

Special Price $64.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Miyayama Y, .et al. Comparative study on the replication of HCV1b genome between wild type and cell culture adaptive mutant in regard to sensitivities against anti-HCV drugs, Microbiol Immunol, 2019, Dec 19 PMID: 31854467

Biological Activity

MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
SCD1 (human) SCD1 (rat) SCD1 (mouse)
1 nM3 nM3 nM
In vitro (25°C) DMSO 89 mg/mL (190.47 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% CMC+0.5% Tween-80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.4 mL 107 mL 214 mL
0.5 mM 4.28 mL 21.4 mL 42.8 mL
1 mM 2.14 mL 10.7 mL 21.4 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11403
Actions Inhibitor
CAS No. 1030612-90-8, 1030612-87-3
Formula C17H16BrFN6O4
M. Wt 467.3
Purity >98%
Synonyms MK8245

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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