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MK-8245

Catalog No.: A11403
SCD inhibitor
Adooq's MK-8245 has been cited by 1 publications
MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
MK-8245
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
2mg
$40.00
In stock
5mg
$90.00
In stock
10mg
$150.00
In stock
25mg
$280.00
In stock
50mg
$480.00
In stock
100mg
$670.00
In stock
10mM * 1mL in DMSO
$75.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's MK-8245 has been cited by 1 publications
  • Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467
    • Biological Activity
    Discription MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A11403
    Formula C17H16BrFN6O4
    Molecular Weight 467.3
    CAS Number 1030612-90-8
    SMILES C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O
    Synonyms MK8245
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 89 mg/mL (190.47 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% CMC+0.5% Tween-80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.4 mL 107 mL 214 mL
    0.5 mM 4.28 mL 21.4 mL 42.8 mL
    1 mM 2.14 mL 10.7 mL 21.4 mL
    5 mM 0.43 mL 2.14 mL 4.28 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Metabolism > Stearoyl-CoA Desaturase (SCD)
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