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$0.00 Biological Activity
Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity sites (Kd = 10 and 270 nM, respectively), stimulating chloride efflux with an EC50 value of 200 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 87.64 mL | 438.21 mL | 876.42 mL |
| 0.5 mM | 17.53 mL | 87.64 mL | 175.28 mL |
| 1 mM | 8.76 mL | 43.82 mL | 87.64 mL |
| 5 mM | 1.75 mL | 8.76 mL | 17.53 mL |
*The above data is based on the productmolecular weight 114.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A14005 |
|---|---|
| Actions | Agonist |
| M. Wt | 114.1 |
| Formula | C4H6N2O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2763-96-4 |
| Synonyms | Agarin, Pantherine |
| SMILES | C1=C(ONC1=O)CN |
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