Muscimol

Catalog No.: A14005

GABAA/GABAC agonist

Muscimol

Muscimol Chemical Structure

CAS NO. 2763-96-4

Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity sites (Kd = 10 and 270 nM, respectively), stimulating chloride efflux with an EC50 value of 200 nM.

Availability: Discontinuted

Package Price
10 mg
$90.00
25 mg
$180.00
50 mg
$320.00
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Biological Activity

Muscimol is a full GABAA agonist and partial GABAC agonist. It binds GABAA on both high- and low-affinity sites (Kd = 10 and 270 nM, respectively), stimulating chloride efflux with an EC50 value of 200 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 87.64 mL 438.21 mL 876.42 mL
0.5 mM 17.53 mL 87.64 mL 175.28 mL
1 mM 8.76 mL 43.82 mL 87.64 mL
5 mM 1.75 mL 8.76 mL 17.53 mL

*The above data is based on the productmolecular weight 114.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14005
Actions Agonist
CAS No. 2763-96-4
Formula C4H6N2O2
M. Wt 114.1
Purity >98%
Synonyms Agarin, Pantherine
SMILES C1=C(ONC1=O)CN
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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