New Products

Catalog No. Product Name Application Information
A17127
YHO-13177
BCRP/ABCG2 inhibitor
YHO-13177 is a potent and specific inhibitor of breast cancer resistance protein (BCRP/ABCG2).
A17142
AG-494
EGFR inhibitor
AG-494 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 1 μM in HT-22 cells.
A17154
SU-5408
VEGFR2 Kinase Inhibitor
SU-5408, also known as VEGFR2 Kinase Inhibitor I, is a potent, cell-permeable inhibitor of mouse VEGFR2 kinase with IC50 value of 70 nM.
A17162
ISCK03
c-kit inhibitor
ISCK03 is a potent c-kit inhibitor.
A17125
CZC-25146
LRRK2 inhibitor
CZC-25146 is a potent LRRK2 inhibitor.
A17129
BIO
GSK3 inhibitor
BIO is a cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3α/β with IC50 value of 5 nM.
A17126
FX1
BCL6 inhibitor
FX1 is an inhibitor of the transcription factor B cell lymphoma 6 (BCL6) with IC50 value of ~35 μM.
A17134
XMD8-87
TNK2 Inhibitor
XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC50 value of 1.9 μM
A17159
TRC051384
Hsp70 inducer
TRC051384 is an inducer of heat shock protein Hsp70.
A17136
TCS-OX2-29 HCl
OX2 receptor antagonist
TCS-OX2-29 is a selective OX2 receptor antagonist with IC50 value of 40 nM. CAS: 1610882-30-8 (HCl) 372523-75-6 (Free Base)
A17122
COH000
SUMO E1 Inhibitor
COH000 is a highly specific covalent allosteric SUMO E1 inhibitor with an IC50 of 0.2 μM for SUMOylation in vitro.
A17153
SU 5205
VEGFR2 inhibitor
SU 5205 is a VEGFR2 inhibitor.
A17065
BCI-121
SMYD3 inhibitor
BCI-121 is an SMYD3 inhibitor. It acts by impairing cancer cell growth.
A17157
SMI-16a
Pim kinase inhibitor
SMI-16a is a selective Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively.
A17014
MZ1
BRD4 protein degrader
MZ1 is a potent inducer of reversible, long-lasting and selective removal of BRD4 over BRD2 and BRD3.
A17130
XMD16-5
TNK2 inhibitor
XMD16-5 is a tyrosine kinase nonreceptor 2(TNK2) inhibitor.
A17117
SKA-31
potassium channel activator
SKA-31 is an activator of KCa2 and KCa3.1 calcium-activated potassium channels.
A17155
KIN-1148
IRF3 agonist
KIN-1148, a small-molecule IRF3 agonist, functions as an influenza vaccine adjuvant by modulating the antiviral immune response.
A17146
AG-126
ERK2 inhibitor
AG-126 is a ERK2 inhibitor that selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM.
A17118
TR-14035
Integrin Antagonist
TR-14035 is a dual antagonist of α4β7 and α4β1 integrins.

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