Nutlin 3b
Important Notice: For research use only. We do not sell to patients.
Loading distributor info...
Important Notice: For research use only. We do not sell to patients.
Loading distributor info...
Discription | Nutlin 3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 uM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a. | ||
---|---|---|---|
Targets |
|
Catalog Num | A11502 |
---|---|
Formula | C30H30Cl2N4O4 |
Molecular Weight | 581.49 |
CAS Number | 675576-97-3 |
SMILES | CC(C)OC1=C(C=CC(=C1)OC)C2=N[C@@H]([C@@H](N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl |
Synonyms | (+)-Nutlin-3, Nutlin-3b |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 90 mg/mL (154.77 mM) | |
Water | Insoluble | ||
Ethanol | 90 mg/mL (154.77 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.2 mL | 85.99 mL | 171.97 mL |
0.5 mM | 3.44 mL | 17.2 mL | 34.39 mL |
1 mM | 1.72 mL | 8.6 mL | 17.2 mL |
5 mM | 0.34 mL | 1.72 mL | 3.44 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2