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IGF-1R inhibitor

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Catalog No. A10658

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NVP-ADW742 5mg A10658-5

Regular Price: €104.50

Special Price: €94.05

NVP-ADW742 10mg A10658-10

Regular Price: €180.50

Special Price: €162.45

NVP-ADW742 50mg A10658-50

Regular Price: €627.00

Special Price: €564.30

NVP-ADW742 100mg A10658-100

Regular Price: €1,187.50

Special Price: €1,068.75

NVP-ADW742 10mM * 1mL in DMSO A10658-10mM-D

Regular Price: €114.00

Special Price: €102.60

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.


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Publications citing Adooq Products
NVP-ADW742 Citations (2)
  • Kazuya Takayama, .et al. Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration, Sci Rep, 2018, 8: 8278 PMID: 29844341
  • Kentaro Hirose, .et al. Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins, BMC Dev Biol, 2014, 14: 42. PMID: 25480380

Chemical Information

Catalog Num A10658
Actions Inhibitor
M. Wt 453.6
Formula C28H31N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 475488-23-4
Synonyms NVPADW742, ADW742, ADW-742, GSK 552602A

Biological Activity

NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.
0.17 μM


Solubility (25°C)* In vitro DMSO 10 mg/mL heating (22.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (6.61 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.05 mL 110.23 mL 220.46mL
0.5 mM 4.41 mL 22.05 mL 44.09 mL
1 mM 2.2 mL 11.02 mL 22.05 mL
5 mM 0.44 mL 2.2 mL 4.41 mL

*The above data is based on the productmolecular weight 453.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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