NVP-BSK805

Catalog No.: A11193

JAK inhibitor

NVP-BSK805 Chemical Structure

CAS NO. 1092499-93-8

NVP-BSK805 is a potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor that potently suppressed recombinant human erythropoietin-induced polycythemia and extramedullary erythropoiesis in mice and rats.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $140.00

Special Price $112.00

10 mg

Regular Price: $200.00

Special Price $160.00

50 mg

Regular Price: $580.00

Special Price $464.00

100 mg

Regular Price: $920.00

Special Price $736.00

10mM * 1mL in DMSO
$217.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NVP-BSK805 is a potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor that potently suppressed recombinant human erythropoietin-induced polycythemia and extramedullary erythropoiesis in mice and rats.

In vitro (25°C) DMSO 113 mg/mL (200.54 mM)
Water 3 mg/mL (5.32 mM)
Ethanol 15 mg/mL (26.62 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.75 mL 88.74 mL 177.47 mL
0.5 mM 3.55 mL 17.75 mL 35.49 mL
1 mM 1.77 mL 8.87 mL 17.75 mL
5 mM 0.35 mL 1.77 mL 3.55 mL

*The above data is based on the productmolecular weight 563.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11193
Actions Inhibitor
M. Wt 563.47
Formula C27H28F2N6O.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1092499-93-8
Synonyms NVPBSK805
SMILES C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F.Cl.Cl

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