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NVP-BSK805 is a potent and selective inhibition of polycythemia by the quinoxaline JAK2 inhibitor that potently suppressed recombinant human erythropoietin-induced polycythemia and extramedullary erythropoiesis in mice and rats.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.75 mL | 88.74 mL | 177.47 mL |
| 0.5 mM | 3.55 mL | 17.75 mL | 35.49 mL |
| 1 mM | 1.77 mL | 8.87 mL | 17.75 mL |
| 5 mM | 0.35 mL | 1.77 mL | 3.55 mL |
*The above data is based on the productmolecular weight 563.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11193 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1092499-93-8 |
| Formula | C27H28F2N6O.2HCl |
| M. Wt | 563.47 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | NVPBSK805 |
| SMILES | C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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