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Biological Activity
Octreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 - 1140 (sst1), 0.4 - 2.1 (sst2), 4.4 - 34.5 (sst3), > 1000 (sst4), and 5.6 - 32 (sst5).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.81 mL | 49.06 mL | 98.11 mL |
| 0.5 mM | 1.96 mL | 9.81 mL | 19.62 mL |
| 1 mM | 0.98 mL | 4.91 mL | 9.81 mL |
| 5 mM | 0.2 mL | 0.98 mL | 1.96 mL |
*The above data is based on the productmolecular weight 1019.24 (free acid). Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12782 |
|---|---|
| Actions | Antagonist |
| CAS No. | 79517-01-4 |
| Formula | C49H66N10O10S2 . xC2H4O2 |
| M. Wt | 1019.24 (free acid) |
| Purity | >98% |
| SMILES | CC(C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CO)C(C)O)O.CC(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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