Oligomycin A

Catalog No.: A10669

ATPase inhibitor

Oligomycin A

Oligomycin A Chemical Structure

CAS NO. 579-13-5

Oligomycin A is a mitochondrial ATPase inhibitor. Oligomycin A inhibits ATP5 (mitochondrial ATPases, F1F0) bound to the cell membrane.

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  • Makoto Kawatani, .et al. Identification of a Small-Molecule Glucose Transporter Inhibitor, Glutipyran, That Inhibits Cancer Cell Growth, ACS Chem Biol, 2021, 16, 8, 1576-1586

Biological Activity

Oligomycin A is a mitochondrial ATPase inhibitor. Oligomycin A inhibits ATP5 (mitochondrial ATPases, F1F0) bound to the cell membrane.
ATP synthase (Cell-free assay)
In vitro (25°C) DMSO 9 mg/mL (11.38 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.64 mL 63.21 mL 126.41 mL
0.5 mM 2.53 mL 12.64 mL 25.28 mL
1 mM 1.26 mL 6.32 mL 12.64 mL
5 mM 0.25 mL 1.26 mL 2.53 mL

*The above data is based on the productmolecular weight 791.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10669
Actions Inhibitor
CAS No. 579-13-5
Formula C45H74O11
M. Wt 791.06
Purity >98%

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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