Ondansetron (Zofran)

Catalog No.: A11701

Ondansetron (Zofran)

Ondansetron (Zofran) Chemical Structure

CAS NO. 99614-02-5

Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting). Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone.

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10 mg
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50 mg
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100 mg
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Biological Activity

Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting). Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone.
In vitro DMSO 0.09 mg/mL (0.31 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.09 mL 170.44 mL 340.88 mL
0.5 mM 6.82 mL 34.09 mL 68.18 mL
1 mM 3.41 mL 17.04 mL 34.09 mL
5 mM 0.68 mL 3.41 mL 6.82 mL

*The above data is based on the productmolecular weight 293.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11701
CAS No. 99614-02-5
Formula C18H19N3O
M. Wt 293.36
Purity >98%
SMILES CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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