P 22077

Catalog No.: A12933
USP7 inhibitor
P 22077 is a cell-permeable inhibitor of the ubiquitin-specific protease (IC?? = 8.6 μM) and the closely related deubiquitinase (DUB) USP47.
Grouped product items
Size Price Stock Qty
2mg
$25.00
In stock
5mg
$45.00
In stock
10mg
$65.00
In stock
25mg
$135.00
In stock
50mg
$215.00
In stock
100mg
$375.00
In stock
10mM * 1mL in DMSO
$85.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Biological Activity
Discription P 22077 is a cell-permeable inhibitor of the ubiquitin-specific protease (IC?? = 8.6 μM) and the closely related deubiquitinase (DUB) USP47.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A12933
Formula C12H7F2NO3S2
Molecular Weight 315.32
CAS Number 1247819-59-5
SMILES CC(=O)C1=CC(=C(S1)SC2=C(C=C(C=C2)F)F)[N+](=O)[O-]
Synonyms P22077
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 57 mg/mL (180.76 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.71 mL 158.57 mL 317.14 mL
0.5 mM 6.34 mL 31.71 mL 63.43 mL
1 mM 3.17 mL 15.86 mL 31.71 mL
5 mM 0.63 mL 3.17 mL 6.34 mL
Useful Calculator

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