p97

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  1. CB5083

    Catalog No. A15827
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    p97 inhibitor
    CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models . Learn More
  2. MSC1094308

    Catalog No. A19120
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    p97/VPS4B inhibitor
    MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively. Learn More
  3. NMS-859

    Catalog No. A21965
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    VCP (p97) inhibitor
    NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively. Learn More
  4. NMS-873

    Catalog No. A12377
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    p97 inhibitor
    NMS-873 is a potent and specific small molecule allosteric inhibitor of the ATPase VCP/p97 (IC50 ~0.03 uM), identified by a high-throughput screening. Learn More
  5. DBeq

    Catalog No. A12736
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    p97 ATPase inhibitor
    Dbeq is a selective and reversible inhibitor of p97 ATPase (IC50 = 1.5 uM). Learn More
  6. ML241

    Catalog No. A15985
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    p97 ATPase inhibitor
    ML241 is a potent and selective inhibitors of p97 ATPase. ML241 inhibit p97 ATPase with IC(50) values of 100 nM. Learn More

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