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PAC-1

Catalog No.: A11090
Caspase activator
Adooq's PAC-1 has been cited by 1 publications
PAC-1 is an activator of procaspase-3 induces apoptosis in cancer cells with EC50 of 2.08 μM.
PAC-1
Grouped product items
Size Price Stock Qty
5mg
$30.00
In stock
10mg
$35.00
In stock
25mg
$70.00
In stock
50mg
$120.00
In stock
100mg
$220.00
In stock
200mg
$420.00
In stock
500mg
$905.00
In stock
10mM * 1mL in DMSO
$25.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PAC-1 has been cited by 1 publications
  • Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168
    • Biological Activity
    Discription PAC-1 is an activator of procaspase-3 induces apoptosis in cancer cells with EC50 of 2.08 μM.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A11090
    Formula C23H28N4O2
    Molecular Weight 392.5
    CAS Number 315183-21-2
    SMILES C=CCC1=CC=C/C(=C/NNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)/C1=O
    Synonyms PAC1,first procaspase activating compound
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 75 mg/mL (191.09 mM)
    Water Insoluble
    Ethanol 15 mg/mL (38.21 mM)
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.48 mL 127.39 mL 254.78 mL
    0.5 mM 5.1 mL 25.48 mL 50.96 mL
    1 mM 2.55 mL 12.74 mL 25.48 mL
    5 mM 0.51 mL 2.55 mL 5.1 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

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    Apoptosis > Caspase
    Proteases > Caspase
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