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Catalog No.: A11152

HDAC inhibitor


PCI-34051 Chemical Structure

CAS NO. 950762-95-5

PCI-34051 is a specific and potent histone deacetylase 8 (HDAC8) inhibitor, with >200-fold selectivity over the other HDAC isoforms.

Availability: In stock

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10 mg
25 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Biological Activity

PCI-34051 is a specific and potent histone deacetylase 8 (HDAC8) inhibitor, with >200-fold selectivity over the other HDAC isoforms.
Target Value
HDAC8IC50: 10nM
HDAC6IC50: 2.9μM
HDAC1IC50: 4μM
HDAC10IC50: 13μM
HDAC2IC50: >50μM
HDAC3IC50: >50μM
In vitro (25°C) DMSO 58 mg/mL (195.73 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+40%PEG300+5% tween80+50% H2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.75 mL 168.75 mL 337.5 mL
0.5 mM 6.75 mL 33.75 mL 67.5 mL
1 mM 3.37 mL 16.87 mL 33.75 mL
5 mM 0.67 mL 3.37 mL 6.75 mL

*The above data is based on the productmolecular weight 296.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11152
Actions Inhibitor
CAS No. 950762-95-5
Formula C17H16N2O3
M. Wt 296.3
Purity >98%
Synonyms PCI34051

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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