PD153035 is an extremely potent and specific inhibitor of the tyrosine kinase activity of EGFR.
Targets
Target
Value
Product Information
Catalog Num
A10702
Formula
C16H14BrN3O2.HCl
Molecular Weight
396.7
CAS Number
183322-45-4
SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl
Synonyms
ZM 252868, AG 1517, Tyrphostin AG 1517, SU 5271
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
0.46 mg/mL (1.16 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
30% propylene glycol, 5% Tween 80, 65% D5W
28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: