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PD153035 (HCl salt)

Catalog No.: A10702
EGFR inhibitor
PD153035 is an extremely potent and specific inhibitor of the tyrosine kinase activity of EGFR.
PD153035 (HCl salt)
Grouped product items
Product Name Price Stock Qty
PD153035 10mg
$50.00
In stock
PD153035 50mg
$220.00
In stock
PD153035 100mg
$380.00
In stock
PD153035 200mg
$630.00
In stock
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Biological Activity
Discription PD153035 is an extremely potent and specific inhibitor of the tyrosine kinase activity of EGFR.
Targets
Target Value
Chemical Information
Catalog Num A10702
Formula C16H14BrN3O2.HCl
Molecular Weight 396.7
CAS Number 183322-45-4
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC.Cl
Synonyms ZM 252868, AG 1517, Tyrphostin AG 1517, SU 5271, PD-153035
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C) DMSO 0.46 mg/mL (1.16 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.21 mL 126.04 mL 252.08 mL
0.5 mM 5.04 mL 25.21 mL 50.42 mL
1 mM 2.52 mL 12.6 mL 25.21 mL
5 mM 0.5 mL 2.52 mL 5.04 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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