Pelitinib (EKB-569)

Pelitinib (EKB-569) is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity.
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Pelitinib 5mg
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Pelitinib 10mg
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Pelitinib 25mg
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Pelitinib 100mg
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Pelitinib (EKB-569) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's Pelitinib (EKB-569) has been cited by 1 publications
  • Shi P, .et al. , Transl Oncol, 2019, Mar 8;12(5):705-713 PMID: 30856555
  • Biological Activity
    Discription Pelitinib (EKB-569) is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity.
    Target Value
    Product Information
    Catalog Num A10706
    Formula C24H23ClFN5O2
    Molecular Weight 467.9
    CAS Number 257933-82-7
    SMILES CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)F)Cl)C#N)NC(=O)/C=C/CN(C)C
    Synonyms WAY-EKB 569

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro DMSO 12 mg/mL (25.64 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.37 mL 106.86 mL 213.72 mL
    0.5 mM 4.27 mL 21.37 mL 42.74 mL
    1 mM 2.14 mL 10.69 mL 21.37 mL
    5 mM 0.43 mL 2.14 mL 4.27 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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