PF-04457845

Catalog No.: A15209

FAAH inhibitor

PF-04457845

PF-04457845 Chemical Structure

CAS NO. 1020315-31-4

PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$300.00
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Biological Activity

PF-04457845 is a potent and exquisitely selective inhibitor of FAAH, with an IC50 of 7.2 nM, and both analgesic and antiinflammatory effects in animal studies comparable to naproxen.
In vitro DMSO 90 mg/mL (197.61 mM)
Water Insoluble
Ethanol 4 mg/mL (8.78 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.96 mL 109.79 mL 219.57 mL
0.5 mM 4.39 mL 21.96 mL 43.91 mL
1 mM 2.2 mL 10.98 mL 21.96 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15209
Actions Inhibitor
CAS No. 1020315-31-4
Formula C23H20F3N5O2
M. Wt 455.43
Purity >98%
Synonyms PF 04457845, PF04457845
SMILES C1CN(CCC1=CC2=CC(=CC=C2)OC3=NC=C(C=C3)C(F)(F)F)C(=O)NC4=NN=CC=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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