PF 4708671

Name: PF 4708671
SKU: A11755
Price: 48 USD
Rating: 5 (2 reviews)

Catalog No.: A11755

S6 kinase inhibitor

Adooq's PF 4708671 has been cited by 2 publications

PF 4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1) that inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 , while having no effect on highly related RSK and MSK kinases.

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Grouped product items
Product Name	Price	Stock
PF 4708671 10mg	Special Price $48.00 Regular Price $60.00	In stock
PF 4708671 25mg	Special Price $96.00 Regular Price $120.00	In stock
PF 4708671 50mg	Special Price $160.00 Regular Price $200.00	In stock
PF 4708671 100mg	Special Price $280.00 Regular Price $350.00	In stock
*PF 4708671 10mM 1mL in DMSO**	Special Price $65.60 Regular Price $82.00	In stock
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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's PF 4708671 has been cited by 2 publications

Amnon Wittenstein, .et al. , PLoS Biol, 2023, Nov 9;21(11):e3002355 PMID: 37943958

Nogami A, .et al. , Transl Oncol, 2018, Nov 22;12(2):336-349 PMID: 30472492

Biological Activity

Discription

Targets

Target	Value

Product Information

Catalog Num	A11755
Formula	C19H21F3N6
Molecular Weight	390.4
CAS Number	1255517-76-0
SMILES	CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F
Synonyms	PF4708671, PF-4708671
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	30 mg/mL (76.84 mM)
	Water	Insoluble
	Ethanol	8 mg/mL (20.49 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.61 mL	128.07 mL	256.15 mL
0.5 mM	5.12 mL	25.61 mL	51.23 mL
1 mM	2.56 mL	12.81 mL	25.61 mL
5 mM	0.51 mL	2.56 mL	5.12 mL

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