PF 573228

Catalog No.: A11235

FAK Inhibitor

PF 573228

PF 573228 Chemical Structure

CAS NO. 869288-64-2

PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $150.00

Special Price $135.00

50 mg

Regular Price: $250.00

Special Price $225.00

100 mg

Regular Price: $400.00

Special Price $360.00

10mM * 1mL in DMSO

Regular Price: $98.00

Special Price $88.20

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).
Targets
FAK (Cell-free assay)
4 nM
In vitro (25°C) DMSO 26 mg/mL (52.9 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.35 mL 101.73 mL 203.46 mL
0.5 mM 4.07 mL 20.35 mL 40.69 mL
1 mM 2.03 mL 10.17 mL 20.35 mL
5 mM 0.41 mL 2.03 mL 4.07 mL

*The above data is based on the productmolecular weight 491.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11235
Actions Inhibitor
M. Wt 491.5
Formula C22H20F3N5O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 869288-64-2
Synonyms PF-573228, PF573228
SMILES CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4

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