PF 573228

Name: PF 573228
SKU: A11235
Price: 40 USD
Rating: 5 (3 reviews)

Catalog No.: A11235

FAK Inhibitor

Adooq's PF 573228 has been cited by 3 publications

PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).

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Grouped product items
Size	Price	Stock
5mg	$40.00	In stock
10mg	$65.00	In stock
25mg	$130.00	In stock
50mg	$220.00	In stock
100mg	$360.00	In stock
500mg	$710.00	In stock
*10mM 1mL in DMSO**	$98.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Adooq Products cited in reputable paper

Adooq's PF 573228 has been cited by 3 publications

Dagyeong Lee, .et al. , J Transl Med, 2024, Feb 14;22(1):154 PMID: 38355577

Izumi D, .et al. , Int J Cancer, 2016, Mar 1;138(5):1207-19 PMID: 26414794

Aya Yokota-Nakatsuma, .et al. , Sci Rep, 2016, 6: 37914 PMID: 27897208

Biological Activity

Discription

PF 573228 is a potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A11235
Formula	C22H20F3N5O3S
Molecular Weight	491.5
CAS Number	869288-64-2
SMILES	CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4
Synonyms	PF-573228, PF573228
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	24 mg/mL (48.83 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+2% Tween 80+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.35 mL	101.73 mL	203.46 mL
0.5 mM	4.07 mL	20.35 mL	40.69 mL
1 mM	2.03 mL	10.17 mL	20.35 mL
5 mM	0.41 mL	2.03 mL	4.07 mL

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