Catalog No.: A10713
c-Met Inhibitor
PHA665752 is a small-molecule inhibitor of c-Met/HGF/SF signaling.
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PHA-665752 5mg
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PHA-665752 10mg
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PHA-665752 50mg
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PHA-665752 100mg
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PHA-665752 10mM * 1mL in DMSO
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Biological Activity
Discription PHA665752 is a small-molecule inhibitor of c-Met/HGF/SF signaling.
Target Value
Product Information
Catalog Num A10713
Formula C32H34Cl2N4O4S
Molecular Weight 641.6
CAS Number 477575-56-7
SMILES CC1=C(NC(=C1C(=O)N2CCC[C@@H]2CN3CCCC3)C)/C=C\4/C5=C(C=CC(=C5)S(=O)(=O)CC6=C(C=CC=C6Cl)Cl)NC4=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 124 mg/mL (193.26 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+castor oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.59 mL 77.93 mL 155.86 mL
0.5 mM 3.12 mL 15.59 mL 31.17 mL
1 mM 1.56 mL 7.79 mL 15.59 mL
5 mM 0.31 mL 1.56 mL 3.12 mL
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