Phosphatase

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  1. Sodium orthovanadate

    Catalog No. A10854
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    Sodium orthovanadate is the chemical compound Na3VO4. It is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue. Learn More
  2. Tautomycetin

    Catalog No. A13049
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    PP1 inhibitor
    Tautomycetin induces apoptosis by inactivating Akt through a PP1-independent signaling pathway in human breast cancer cells. Learn More
  3. Sephin1

    Catalog No. A12791
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    PPP1R15A inhibitor
    Sephin1 is a selective inhibitor of stress-induced PPP1R15A and targets disease associated with accumulation of misfolded protein. Learn More
  4. LB-100

    Catalog No. A11597
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    PP2A inhibitor
    LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. Learn More
  5. NSC 95397

    Catalog No. A11470
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    Phosphatase inhibitor
    NSC 95397 is a selective and effective dual-specificity, quinone-based phosphatase inhibitor. Learn More
  6. NSC 87877

    Catalog No. A15384
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    SHP1/2 PTPase Inhibitor
    NSC 87877 is a potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1). Learn More
  7. Alexidine dihydrochloride

    Catalog No. A15382
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    PTPMT1 inhibitor
    Alexidine is an alkyl bis(biguanide) antiseptic which has been used in mouthwashes to eliminate plaque forming microorganisms. Learn More
  8. Fumonisin B1

    Catalog No. A15379
    serine/threonine phosphatase inhibitor
    Fumonisin B1 is a fungal metabolite produced by Fusarium moniliforme, that has been shown to inhibit protein serine/threonine phosphatases (PP1, PP2A, PP2B, PP2C, and PP5/T/K/H), and is most effective with PP5. Learn More
  9. Ceramide

    Catalog No. A15377
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    Ser/Thr protein phosphatase activator
    Ceramide is a ceramide shown to be a potent modulator of proliferation and differentiation, used as a tool for studying the complex signaling associated with the ceramides. Learn More
  10. Microcystin-LR

    Catalog No. A14310
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    protein phosphatase inhibitor
    Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. Learn More
  11. Sal003

    Catalog No. A14305
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    eIF2α phosphatase inhibitor
    Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor. Learn More
  12. CCT007093

    Catalog No. A14289
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    CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. Learn More
  13. (-)-p-Bromotetramisole Oxalate

    Catalog No. A14271
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    phosphatase inhibitor
    (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor. Learn More
  14. NSC87877

    Catalog No. A16120
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    SHP inhibitor
    NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. Learn More

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