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AKT Inhibitor

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Catalog No. A11032

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PHT-427 10mg A11032-10

Regular Price: €47.50

Special Price: €42.75

PHT-427 50mg A11032-50

Regular Price: €209.00

Special Price: €188.10

PHT-427 100mg A11032-100

Regular Price: €323.00

Special Price: €290.70

PHT-427 200mg A11032-200

Regular Price: €570.00

Special Price: €513.00

PHT-427 10mM * 1mL in DMSO A11032-10mM-D

Regular Price: €52.25

Special Price: €47.03

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PHT-427 is a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.


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Chemical Information

Catalog Num A11032
Actions Inhibitor
M. Wt 409.6
Formula C20H31N3O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1191951-57-1
Synonyms PHT427

Biological Activity

PHT-427 is a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.
Akt PDK-1
2.7 μM(Ki)5.2 μM(Ki)


Solubility (25°C) * In vitro DMSO 82 mg/mL (200.19 mM)
Water <1 mg/mL (<1 mM)
Ethanol 60 mg/mL (146.48 mM)
In vivo 5% DMSO/95% Corn oil 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.41 mL 122.07 mL 244.14mL
0.5 mM 4.88 mL 24.41 mL 48.83 mL
1 mM 2.44 mL 12.21 mL 24.41 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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