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Catalog No.: A11032

AKT Inhibitor


PHT-427 Chemical Structure

CAS NO. 1191951-57-1

PHT-427 is a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $50.00

Special Price $40.00

50 mg

Regular Price: $220.00

Special Price $176.00

100 mg

Regular Price: $340.00

Special Price $272.00

200 mg

Regular Price: $600.00

Special Price $480.00

10mM * 1mL in DMSO

Regular Price: $55.00

Special Price $44.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PHT-427 is a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor.
Akt PDK-1
2.7 μM(Ki)5.2 μM(Ki)
In vitro (25°C) DMSO 75 mg/mL (183.1 mM)
Water Insoluble
Ethanol 55 mg/mL (134.27 mM)
In vivo 5% DMSO+95% Corn oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.41 mL 122.07 mL 244.14 mL
0.5 mM 4.88 mL 24.41 mL 48.83 mL
1 mM 2.44 mL 12.21 mL 24.41 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11032
Actions Inhibitor
CAS No. 1191951-57-1
Formula C20H31N3O2S2
M. Wt 409.6
Purity >98%
Synonyms PHT427

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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