PIK-294

Catalog No.: A10728

PI3K inhibitor

PIK-294

PIK-294 Chemical Structure

CAS NO. 900185-02-6

PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
50 mg
$350.00
100 mg
$550.00
10mM * 1mL in DMSO
$100.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110δ-selective inhibitors that has been reported.
Targets
p110δ p110γ p110β
10 nM160 nM490 nM
In vitro DMSO 98 mg/mL (200.19 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.43 mL 102.15 mL 204.29 mL
0.5 mM 4.09 mL 20.43 mL 40.86 mL
1 mM 2.04 mL 10.21 mL 20.43 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10728
Actions Inhibitor
M. Wt 489.5
Formula C28H23N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 900185-02-6
Synonyms PIK294
SMILES CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=C(C(=N4)C6=CC(=CC=C6)O)C(=NC=N5)N

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