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Biological Activity
Pimobendan (Vetmedin) is a calcium sensitizer with positive inotropic and vasodilator effects. It is also a selective inhibitor of phosphodiesterase III (PDE3).
Targets
| PDE3 | ||||
| 0.32 μM |
| In vitro (25°C) | DMSO | 62 mg/mL (185.42 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (14.95 mM) | ||
| In vivo | 0.5% methylcellulose | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.9 mL | 149.52 mL | 299.04 mL |
| 0.5 mM | 5.98 mL | 29.9 mL | 59.81 mL |
| 1 mM | 2.99 mL | 14.95 mL | 29.9 mL |
| 5 mM | 0.6 mL | 2.99 mL | 5.98 mL |
*The above data is based on the productmolecular weight 334.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10733 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 74150-27-9 |
| Formula | C19H18N4O2 |
| M. Wt | 334.4 |
| Purity | >98% |
| Synonyms | Vetmedin, Acardi, pimobendane |
| SMILES | CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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