Pimobendan (Vetmedin)

Catalog No.: A10733

PDE inhibitor

Pimobendan (Vetmedin)

Pimobendan (Vetmedin) Chemical Structure

CAS NO. 74150-27-9

Pimobendan (Vetmedin) is a calcium sensitizer with positive inotropic and vasodilator effects. It is also a selective inhibitor of phosphodiesterase III (PDE3).

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
50 mg
$580.00
100 mg
$980.00
10mM * 1mL in DMSO
$139.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Pimobendan (Vetmedin) is a calcium sensitizer with positive inotropic and vasodilator effects. It is also a selective inhibitor of phosphodiesterase III (PDE3).
Targets
PDE3
0.32 μM
In vitro (25°C) DMSO 67 mg/mL (200.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol 5 mg/mL (14.95 mM)
In vivo 0.5% methylcellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.9 mL 149.52 mL 299.04 mL
0.5 mM 5.98 mL 29.9 mL 59.81 mL
1 mM 2.99 mL 14.95 mL 29.9 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10733
Actions Inhibitor
M. Wt 334.4
Formula C19H18N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 74150-27-9
Synonyms Vetmedin, Acardi, pimobendane
SMILES CC1CC(=O)NN=C1C2=CC3=C(C=C2)N=C(N3)C4=CC=C(C=C4)OC

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