Total item
Cart Subtotal
$0.00 Biological Activity
PR-619 is a cell-permeable, reversible, and broad-spectrum inhibitor of the deubiquitinylating enzymes (DUBs).
Targets
| Target | Value |
|---|---|
| JOSD2 | EC50: 1.17μM |
| SENP6core | EC50: 2.37μM |
| UCH-L3 | EC50: 2.95μM |
| USP4 | EC50: 3.93μM |
| USP8 | EC50: 4.90μM |
| DEN1 | EC50: 4.98μM |
| USP20 | EC50: 5.10μM |
| USP28 | EC50: 6.24μM |
| USP7 | EC50: 6.86μM |
| USP2core | EC50: 7.20μM |
| USP15 | EC50: 8.23μM |
| USP5 | EC50: 8.61μM |
| USP47 | EC50: 8.87μM |
| UCH-L5 | EC50: 9.26μM |
| UCH-L1 | EC50: 12.8μM |
| Plpro | EC50: 14.2μM |
| PLA2 | EC50: >50μM |
| Calpain1 | EC50: >50μM |
| CT-L | EC50: >50μM |
| CathepsinD | EC50: >50μM |
| MMP13 | EC50: >50μM |
| Trypsin | EC50: >50μM |
| In vitro | DMSO | 45 mg/mL (201.54 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 44.79 mL | 223.93 mL | 447.87 mL |
| 0.5 mM | 8.96 mL | 44.79 mL | 89.57 mL |
| 1 mM | 4.48 mL | 22.39 mL | 44.79 mL |
| 5 mM | 0.9 mL | 4.48 mL | 8.96 mL |
*The above data is based on the productmolecular weight 223.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13190 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 223.28 |
| Formula | C7H5N5S2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2645-32-1 |
| Synonyms | PR619, PR 619 |
| SMILES | C1=C(C(=NC(=C1SC#N)N)N)SC#N |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy PR-619 | PR-619 Supplier | purchase PR-619 | PR-619 cost | PR-619 manufacturer | order PR-619 | PR-619 distributor | buy 2645-32-1| 2645-32-1 Supplier | purchase 2645-32-1 | 2645-32-1 cost | 2645-32-1 manufacturer | order 2645-32-1 | 2645-32-1 distributor
Adooq Quality Guarantee
We promise all products perform as described.