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Items 151 to 200 of 1755 total

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Catalog No. Product Name Application Product Information Sale Price

LY2603618 (IC-83) SALE

Chk inhibitor
LY2603618 is a chk2 inhibitor that binds to and inhibits the activity of chk2, which may prevent the repair of DNA caused by DNA-damaging agents.

Special Price Starting at: $81.00


VX-765 (Belnacasan) SALE

Caspase-1/4 inhibitor
VX-765 is a novel Caspase-1 inhibitor,which is an enzyme that controls the generation of two cytokines, IL-1b and IL-18.

Special Price Starting at: $63.00


Vorinostat (SAHA) SALE

HDAC inhibitor
Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.

Special Price Starting at: $40.50


Droxinostat SALE

HDAC inhibitor
Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 that shows comparable inhibition of HDAC6 and HDAC8 with IC50 = 2.47 and 1.46 μmol/L, respectively.

Special Price Starting at: $36.00


MK-1775 SALE

WEE1 Inhibitor
MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.

Special Price Starting at: $63.00


Moxifloxacin HCl SALE

Topoisomerase inhibitor
Moxifloxacin is a quinolone/fluoroquinolone antibiotic.

Special Price Starting at: $40.50


Tandutinib (MLN518) SALE

FLT3 Inhibitor
Tandutinib (MLN518) inhibits the autophosphorylation of FLT3, c-KIT and PDGF receptor tyrosine kinases, thereby inhibiting cellular proliferation and inducing apoptosis.

Special Price Starting at: $36.00


SB 203580 SALE

p38 MAPK inhibitor
SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.

Special Price Starting at: $45.00


SB 431542 SALE

TGF-beta/Smad inhibitor
SB 431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7 .

Special Price Starting at: $72.00


WYE-125132 (WYE-132) SALE

mTOR Inhibitor
WYE-125132 is an ATP-competitive and specific inhibitor of mTORC1 and mTORC2 (IC50 = 0.19 nM; >5,000-fold selective versus PI3Ks).

Special Price Starting at: $108.00



Aurora A Inhibitor
MLN8054 is an inhibitor of Aurora A kinase, induces senescence in human tumor cells both in vitro and in vivo.

Special Price Starting at: $90.00



Wnt/beta-catenin inhibitor
ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .

Special Price Starting at: $54.00


Caffeic acid SALE

Caffeic acid is an organic compound that is classified as hydroxycinnamic acid.

Special Price Starting at: $36.00


BIX 02189 SALE

MEK inhibitor
BIX 02189 is a selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1 and other closely related kinases respectively.

Special Price Starting at: $81.00



MEK Inhibitor
TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.

Special Price Starting at: $81.00


Baicalin SALE

HIV-1 production Inhibitor
Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors.

Special Price Starting at: $45.00


CP-690550 (Tofacitinib citrate) SALE

JAK3 inhibitor
CP-690550 (Tofacitinib citrate) is an orally available, highly selective inhibitor of the Janus kinase (JAK) family of enzymes.

Special Price Starting at: $54.00


Daptomycin SALE

DNA/RNA Synthesis inhibitor
Daptomycin is a lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms.

Special Price Starting at: $45.00


SNS-032 (BMS-387032) SALE

CDK inhibitor
SNS-032 (BMS-387032) is a highly selective and potent inhibitor of cyclin-dependent kinases (Cdks) 2, 7, and 9, with in vitro growth inhibitory effects and ability to induce apoptosis in malignant B cells.

Special Price Starting at: $36.00


Danoprevir (RG7227) SALE

HCV NS3/4A protease inhibitor
Danoprevir is a potent inhibitor of the HCV NS3/4A serine protease.

Special Price Starting at: $54.00



ALK Inhibitor
TAE684 is a inhibitor of ALK and also a potent inhibitor of LRRK2 kinase activity (IC(50) of 7.8nM against wild-type LRRK2, 6.1nM against the G2019S mutant).

Special Price Starting at: $72.00


PCI-24781 (Abexinostat) SALE

HDAC Inhibitor
PCI-24781 is a broad-spectrum phenyl hydroxamic acid HDAC inhibitor.

Special Price Starting at: $72.00


Brivanib (BMS-540215) SALE

VEGFR-2 inhibitor
Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.

Special Price Starting at: $81.00


Fulvestrant (Faslodex) SALE

Aromatase inhibitor
Fulvestrant is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.

Special Price Starting at: $45.00


Doramapimod (BIRB-796) SALE

p38 MAPK inhibitor
Doramapimod (BIRB 796) is a small molecule inhibitor of p38 MAPK,which plays a critical role in regulating the production of proinflammatory cytokines.

Special Price Starting at: $27.00



PI3K inhibitor
XL765 is a PI3K/mTOR dual kinase inhibitor and it is more potent compared to an agent that inhibits either PI3K kinase or mTOR kinase alone.

Special Price Starting at: $81.00


Bleomycin sulfate SALE

DNA/RNA Synthesis inhibitor
Bleomycin sulfate is a mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus.

Special Price Starting at: $90.00


Dienogest SALE

Dienogest is an oral progestin that has antiandrogenic activity and as a result can improve androgenic symptoms.

Special Price Starting at: $63.00


Tubastatin A HCl SALE

HDAC6 inhibitor
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).

Special Price Starting at: $54.00


Bosutinib (SKI-606) SALE

Src inhibitor
Bosutinib (SKI-606) is a tyrosine kinase inhibitor undergoing research for use in the treatment of cancer.

Special Price Starting at: $49.50



Proteasome inhibitor
MG-132 is a potent cell-permeable inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 μM).

Special Price Starting at: $45.00


Fluorouracil (Adrucil) SALE

DNA and RNA synthesis inhibitor
Fluorouracil (Adrucil) is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase.

Special Price Starting at: $36.00


Gemcitabine HCl (Gemzar) SALE

DNA/RNA Synthesis inhibitor
Gemcitabine (Gemzar) is a newer chemotherapy drug acting by replacing one of the building blocks of nucleic acids during DNA replication in cancer cells, preventing tumor growth.

Special Price Starting at: $27.00


Maraviroc (UK-427857) SALE

CCR antagonist
Maraviroc is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection.

Special Price Starting at: $36.00


Vicriviroc Malate SALE

CCR5 antagonist
Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC50 =0.46 nM and IC50 =1~10 nM to HIV isolates (n=52).

Special Price Starting at: $108.00


PHA-793887 SALE

CDK Inhibitor
PHA-793887, a novel potent inhibitor of Cdk, target on kinds of cyclin-dependent kinase under low concentrations and poses high activity against several cancer cell lines.

Special Price Starting at: $81.00



CDK Inhibitor
AT7519 is an inhibitor of multiple cyclin-dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation.

Special Price Starting at: $63.00



CDK inhibitor
BS-181 HCl is a potential anti-tumor agent as CDK7 inhibitor.

Special Price Starting at: $126.00


Flavopiridol HCl SALE

CDK inhibitor
Flavopiridol HCl is an inhibitor of cyclin-dependent kinases. The (-)-cis form induces apoptosis in particular tumor cells.

Special Price Starting at: $54.00



CHK Inhibitor
CHIR-124 is a novel and potent Chk1 inhibitor (IC50: 0.32 nM and 697 nM for Chk1 and Chk2 respectively).

Special Price Starting at: $63.00


Chrysophanic acid (Chrysophanol) SALE

EGFR inhibitor
Chrysophanic acid (Chrysophanol) blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway.

Special Price Starting at: $36.00


Icariin SALE

PDE5 inhibitor
Icariin is inhibitory to all three PDE5 isoforms that inhibits PDE5A1, A2, and A3 with an IC50 value of 1.0, 0.75, and 1.1 microM, respectively.

Special Price Starting at: $54.00


LY2940680 (Taladegib) SALE

SMO Antagonist
LY2940680 has been shown to affect a cancer cell signaling pathway initiated by the Hedgehog (Hh) protein.

Special Price Starting at: $99.00


OSU-03012 SALE

PDK-1 inhibitor
OSU-03012 is a novel celecoxib derivative, without cyclooxygenase-2 inhibitory activity, capable of inducing apoptosis in various cancer cells types.

Special Price Starting at: $45.00



FAAH inhibitor
URB597 is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH).

Special Price Starting at: $36.00


Decitabine SALE

DNA Methyltransferase Inhibitors
Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.

Special Price Starting at: $36.00


SB 202190 SALE

p38 MAPK Inhibitor
SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase.

Special Price Starting at: $36.00


Raltegravir (MK-0518) SALE

HIV-1 integrase inhibitor
Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.

Special Price Starting at: $63.00


Silibinin (Silybin) SALE

Silibinin (silybin) is the major active constituent of silymarina compound extracted from the seeds of the herb milk thistle.

Special Price Starting at: $40.50


Geldanamycin SALE

Hsp90 inhibitor
Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity.

Special Price Starting at: $54.00

Items 151 to 200 of 1755 total

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