Products On Sale

5 Item(s)

per page

Set Descending Direction
  1. GSK126

    Catalog No. A11757
    Quick View
    EZH2 inhibitor
    GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity, decreases global H3K27me3 levels and reactivates silenced PRC2 target genes. Learn More
  2. EPZ-6438 (Tazemetostat)

    Catalog No. A12712
    Quick View
    EZH2 inhibitor
    EPZ-6438 is a potent, selective, and orally bioavailable small-molecule inhibitor of EZH2 enzymatic activity. It induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells. Learn More
  3. GSK343

    Catalog No. A13114
    Quick View
    EZH2 inhibitor
    GSK343 is a potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC= 4 nM). Diplays 1000-fold selectivity for other HMTs except EZH1 (60-fold selectivity). GSK343 inhibits H3K27 methylation in HCC1806 cells with an IC of <200nM (measured by immunofluorescence). Learn More
  4. CPI-169

    Catalog No. A15920
    Quick View
    EZH2 inhibitor
    CPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively. Learn More
  5. UNC-1999

    Catalog No. A13166
    Quick View
    EZH2/EZH1 Inhibitor
    UNC1999 is the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1. Learn More

5 Item(s)

per page

Set Descending Direction
Rewards