Proteases

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  1. gamma-secretase modulator

    E 2012 is γ-secretase inhibitor.
  2. Gamma-secretase modulator

    gamma-secretase modulator 1 is a gamma-secretase modulator, gamma-secretase modulator 1 is useful for Alzheimer's disease.
  3. Gamma-secretase modulator

    gamma-secretase modulator 2 is a potent and selective gamma-secretase modulator for treatment of Alzheimer's disease.
  4. gamma-secretase modulator

    Flurizan is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits γ-secretase activity.
  5. Gamma-secretase modulator

    TC-E 5006 is a gamma-secretase modulator. Reduces Aβ42 levels in vitro (EC50 = 390 nM) and in vivo.
  6. gamma-secretase modulator

    gamma-secretase modulator 3 is a gamma-secretase modulator.
  7. Gamma-secretase modulator

    Compound W is a γ-secretase inhibitor that has been shown to lower the levels of secreted Aβ42 and Nβ25.
  8. γ-Secretase modulator

    CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively.
  9. γ-Secretase Modulator

    NGP-555 is a gamma-secretase modulator with a selective mechanism to reduce Abeta 42 while raising shorter Abeta forms such as Abeta 37 and 38.
  10. γ-secretase modulator

    BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively.
  11. γ secretase modulator

    BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for Aβ42.
  12. tyrosine kinase signal transduction modulator

    SU 4942 is a tyrosine kinase signal transduction modulator, targeting VEGF and ECGF.

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