Protein Tyrosine Phosphatase

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  1. SF1670

    Catalog No. A13475
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    PTEN inhibitor
    SF1670 is a selective PTEN inhibitor (IC50=2 uM). As PTEN-mTOR pathway is critical for controlling the regenerative capacity of corticospinal neurons, PTEN deletion or its inhibitor enhances the regenerative ability of adult corticospinal neurons. Pretreatment with SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model. Learn More
  2. Shikonin

    Catalog No. A12125
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    PTEN Inhibitor
    Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1. Learn More
  3. Bakuchiol

    Catalog No. A14770
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    Bakuchiol is an antioxidant inhibitor of protein tyrosine phosphatase 1B (PTP1B). Learn More
  4. BVT 948

    Catalog No. A15383
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    PTP inhibitor
    BVT 948 is a non-competitive PTP (protein tyrosine phosphatase) inhibitor. Learn More
  5. TCS 401 free base

    Catalog No. A15390
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    PTP1B Inhibitor
    TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) (Ki values are 0.29, 59, 560, 1100, > 2000, > 2000 and > 2000 μM for PTP1B, CD45 D1D2, PTPβ, PTPε D1, SHP-1, PTPα D1 and LAR D1D2 respectively). Learn More
  6. PTP1B-IN-1

    Catalog No. A22000
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    PTP1B inhibitor
    PTP1B-IN-1 is a potent protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 1.6 mM; 1,2,5-thiadiazolidin-3-one-1,1-dioxide scaffold for derivatives synthesis. Learn More
  7. PTP1B-IN-3

    Catalog No. A21149
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    PTP1B inhibitor
    PTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively. Learn More
  8. PTP1B-IN-8

    Catalog No. A19109
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    PTP1B inhibitor
    PTP1B-IN-8 is a potent and selective potent protein tyrosine phosphatase-1B (PTP1B) inhibitor extracted from patent CN103626692A, example 1. Learn More
  9. DPM-1001

    Catalog No. A18674
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    PTP1B inhibitor
    DPM-1001 is a potent, specific, orally bioavailable and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM, an an analog of the specific PTP1B inhibitor trodusquemine (MSI-1436; IC50=600 nM). DPM-1001 has anti-diabetic property. Learn More
  10. TCS 401

    Catalog No. A21859
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    PTP1B inhibitor
    TCS 401 is a selective inhibitor of protein tyrosine phosphatase 1B (PTP1B). Learn More

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