Purmorphamine

Catalog No.: A11480

Hedgehog signaling activator

Purmorphamine

Purmorphamine Chemical Structure

CAS NO. 483367-10-8

Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts.

Availability: In stock

Package Price Qty
5 mg
$75.00
10 mg
$140.00
25 mg
$300.00
50 mg
$520.00
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Biological Activity

Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts.
Targets
Smoothened (HEK293T cells)
~1.5 μM
In vitro (25°C) DMSO Warmed: 4 mg/mL (7.68 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.21 mL 96.04 mL 192.09 mL
0.5 mM 3.84 mL 19.21 mL 38.42 mL
1 mM 1.92 mL 9.6 mL 19.21 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11480
Actions Activator
CAS No. 483367-10-8
Formula C31H32N6O2
M. Wt 520.6
Purity >98%
SMILES C1CCC(CC1)N2C=NC3=C2N=C(N=C3NC4=CC=C(C=C4)N5CCOCC5)OC6=CC=CC7=CC=CC=C76
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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