Raltegravir (MK-0518)

Catalog No.: A10775

HIV-1 integrase inhibitor

Raltegravir (MK-0518)

Raltegravir (MK-0518) Chemical Structure

CAS NO. 518048-05-0

Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.

Availability: In stock

Package Price Qty
5 mg
$45.00
10 mg
$65.00
50 mg
$160.00
100 mg
$255.00
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  • Lea El Khoury, .et al. Spectrometric and computational studies of the binding of HIV-1 integrase inhibitors to viral DNA extremities, PeerJ Preprints, 2019, 7:e27833v1

Biological Activity

Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.5 mL 112.51 mL 225.02 mL
0.5 mM 4.5 mL 22.5 mL 45 mL
1 mM 2.25 mL 11.25 mL 22.5 mL
5 mM 0.45 mL 2.25 mL 4.5 mL

*The above data is based on the productmolecular weight 444.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10775
Actions Inhibitor
M. Wt 444.4
Formula C20H21FN6O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 518048-05-0
Synonyms Isentress, MK0518, MK-0518
SMILES CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)[O-])C(=O)NCC3=CC=C(C=C3)F.[K+]

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