Retigabine (Ezogabine)

Catalog No.: A11922

Retigabine (Ezogabine)

Retigabine (Ezogabine) Chemical Structure

CAS NO. 150812-12-7

Retigabine is an anticonvulsant used as a treatment for partial epilepsies.

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25 mg
$140.00
50 mg
$220.00
100 mg
$400.00
250 mg
$900.00
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  • Vigil FA, .et al. Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, “M-type”) K+ currents in neurons, J Cereb Blood Flow Metab, 2019, Jul 4:271678X19857818 PMID: 31272312
  • Joseph Lombardo, .et al. Nonreciprocal mechanisms in up- and downregulation of spinal motoneuron excitability by modulators of KCNQ/Kv7 channels, J Neurophysiol, 2016, Nov 1; 116(5): 2114–2124 PMID: 27512022
  • Sonya M. Bierbower, .et al. Augmentation of M-Type (KCNQ) Potassium Channels as a Novel Strategy to Reduce Stroke-Induced Brain Injury, J Neurosci, 2015, Feb 4; 35(5): 2101–2111 PMID: 25653366

Biological Activity

Retigabine is an anticonvulsant used as a treatment for partial epilepsies.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.97 mL 164.83 mL 329.66 mL
0.5 mM 6.59 mL 32.97 mL 65.93 mL
1 mM 3.3 mL 16.48 mL 32.97 mL
5 mM 0.66 mL 3.3 mL 6.59 mL

*The above data is based on the productmolecular weight 303.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11922
M. Wt 303.34
Formula C16H18FN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 150812-12-7
SMILES CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N

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