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RG3039 (PF-06687859) is an orally bioavailable and brain-penetrant DcpS inhibitor with an IC50 of 0.069 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.13 mL | 115.65 mL | 231.29 mL |
| 0.5 mM | 4.63 mL | 23.13 mL | 46.26 mL |
| 1 mM | 2.31 mL | 11.56 mL | 23.13 mL |
| 5 mM | 0.46 mL | 2.31 mL | 4.63 mL |
*The above data is based on the productmolecular weight 432.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12642 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 432.35 |
| Formula | C21H23Cl2N5O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1005504-62-0 |
| Synonyms | RG 3039, RG-3039, PF-06687859, PF06687859, PF 06687859 |
| SMILES | NC1=NC(N)=C2C(OCC3CCN(CC4=C(Cl)C=CC=C4Cl)CC3)=CC=CC2=N1 |
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