Rilpivirine (R 278474, TMC 278)

Catalog No.: A11542

NNRT inhibitor

Rilpivirine (R 278474, TMC 278)

Rilpivirine (R 278474, TMC 278) Chemical Structure

CAS NO. 500287-72-9

Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $140.00

Special Price $126.00

25 mg

Regular Price: $240.00

Special Price $216.00

50 mg

Regular Price: $390.00

Special Price $351.00

10mM * 1mL in DMSO

Regular Price: $110.00

Special Price $99.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
In vitro DMSO 73 mg/mL (199.22 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.29 mL 136.46 mL 272.93 mL
0.5 mM 5.46 mL 27.29 mL 54.59 mL
1 mM 2.73 mL 13.65 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11542
Actions Inhibitor
M. Wt 366.4
Formula C22H18N6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 500287-72-9
Synonyms R278474, TMC278, TMC-278
SMILES CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N

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