Rilpivirine (R 278474, TMC 278)

Catalog No.: A11542

NNRT inhibitor

Rilpivirine (R 278474, TMC 278)

Rilpivirine (R 278474, TMC 278) Chemical Structure

CAS NO. 500287-72-9

Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.

Availability: In stock

Package Price Qty
10 mg
$140.00
25 mg
$240.00
50 mg
$390.00
10mM * 1mL in DMSO
$110.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
In vitro DMSO 66 mg/mL (180.12 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.29 mL 136.46 mL 272.93 mL
0.5 mM 5.46 mL 27.29 mL 54.59 mL
1 mM 2.73 mL 13.65 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11542
Actions Inhibitor
CAS No. 500287-72-9
Formula C22H18N6
M. Wt 366.4
Purity >98%
Synonyms R278474, TMC278, TMC-278
SMILES CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Rilpivirine (R 278474, TMC 278) | Rilpivirine (R 278474, TMC 278) Supplier | purchase | cost | manufacturer | order | distributor | buy 500287-72-9 | 500287-72-9 Supplier | purchase 500287-72-9 | 500287-72-9 cost | 500287-72-9 manufacturer | order 500287-72-9 | 500287-72-9 distributor
Rewards