Rilpivirine (R 278474, TMC 278)

Catalog No.: A11542
NNRT inhibitor
Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
Grouped product items
Product Name Price Stock Qty
Rilpivirine 10mg
Special Price $112.00 Regular Price $140.00
In stock
Rilpivirine 25mg
Special Price $192.00 Regular Price $240.00
In stock
Rilpivirine 50mg
Special Price $312.00 Regular Price $390.00
In stock
Rilpivirine 10mM * 1mL in DMSO
Special Price $88.00 Regular Price $110.00
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Biological Activity
Discription Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
Product Information
Catalog Num A11542
Formula C22H18N6
Molecular Weight 366.4
CAS Number 500287-72-9
SMILES CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
Synonyms R278474, TMC278, TMC-278
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 66 mg/mL (180.12 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.29 mL 136.46 mL 272.93 mL
0.5 mM 5.46 mL 27.29 mL 54.59 mL
1 mM 2.73 mL 13.65 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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