Ro 61-8048

Catalog No.: A12833

Hydroxylase Inhibitor

Ro 61-8048

Ro 61-8048 Chemical Structure

CAS NO. 199666-03-0

Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM).

Availability: In stock

Package Price Qty
10 mg
$70.00
25 mg
$130.00
50 mg
$200.00
100 mg
$320.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM).
Targets
KMO KMO
4.8 nM(Ki)37 nM
In vitro (25°C) DMSO 80 mg/mL (189.82 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.73 mL 118.64 mL 237.28 mL
0.5 mM 4.75 mL 23.73 mL 47.46 mL
1 mM 2.37 mL 11.86 mL 23.73 mL
5 mM 0.47 mL 2.37 mL 4.75 mL

*The above data is based on the productmolecular weight 421.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12833
Actions Inhibitor
CAS No. 199666-03-0
Formula C17H15N3O6S2
M. Wt 421.45
Solubility DMSO
Purity >98%
Synonyms Ro61-8048
SMILES COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Ro 61-8048 | Ro 61-8048 Supplier | purchase | cost | manufacturer | order | distributor | buy 199666-03-0| 199666-03-0 Supplier | purchase 199666-03-0 | 199666-03-0 cost | 199666-03-0 manufacturer | order 199666-03-0 | 199666-03-0 distributor
Rewards