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Ro 61-8048

Catalog No.: A12833

Hydroxylase Inhibitor

Ro 61-8048

Ro 61-8048 Chemical Structure

CAS NO. 199666-03-0

Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM).

Availability: In stock

Package Price Qty
10 mg
$70.00
25 mg
$130.00
50 mg
$200.00
100 mg
$320.00
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Biological Activity

Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM).
Targets
KMO KMO
4.8 nM(Ki)37 nM
In vitro (25°C) DMSO 80 mg/mL (189.82 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.73 mL 118.64 mL 237.28 mL
0.5 mM 4.75 mL 23.73 mL 47.46 mL
1 mM 2.37 mL 11.86 mL 23.73 mL
5 mM 0.47 mL 2.37 mL 4.75 mL

*The above data is based on the productmolecular weight 421.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12833
Actions Inhibitor
CAS No. 199666-03-0
Formula C17H15N3O6S2
M. Wt 421.45
Purity >98%
Synonyms Ro61-8048
SMILES COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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