ROCK inhibitor

Catalog No.: A15225

ROCK inhibitor

ROCK inhibitor

ROCK inhibitor Chemical Structure

CAS NO. 867017-68-3

ROCK inhibitor is a highly potent inhibitor of human ROCK-1 and ROCK-2 isoenzymes with IC50 values of 0.6 and 1.1 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$300.00
10 mg
$450.00
50 mg
$1,100.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ROCK inhibitor is a highly potent inhibitor of human ROCK-1 and ROCK-2 isoenzymes with IC50 values of 0.6 and 1.1 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.83 mL 124.13 mL 248.27 mL
0.5 mM 4.97 mL 24.83 mL 49.65 mL
1 mM 2.48 mL 12.41 mL 24.83 mL
5 mM 0.5 mL 2.48 mL 4.97 mL

*The above data is based on the productmolecular weight 402.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A15225
Actions Inhibitor
M. Wt 402.79
Formula C18H13ClF2N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 867017-68-3
Synonyms Rho-kinase inhibitor, Rho Kinase Inhibitor, ROCK
SMILES CC1=CNC2=NC=CC(=C12)OC3=C(C=C(C=C3F)NC4=CC(=NC(=N4)N)Cl)F

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