ROCK inhibitor
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | ROCK inhibitor is a highly potent inhibitor of human ROCK-1 and ROCK-2 isoenzymes with IC50 values of 0.6 and 1.1 nM, respectively. | ||
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Targets |
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Catalog Num | A15225 |
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Formula | C18H13ClF2N6O |
Molecular Weight | 402.79 |
CAS Number | 867017-68-3 |
SMILES | CC1=CNC2=NC=CC(=C12)OC3=C(C=C(C=C3F)NC4=CC(=NC(=N4)N)Cl)F |
Synonyms | Rho-kinase inhibitor, Rho Kinase Inhibitor, ROCK |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 77 mg/mL (191.16 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (4.96 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.83 mL | 124.13 mL | 248.27 mL |
0.5 mM | 4.97 mL | 24.83 mL | 49.65 mL |
1 mM | 2.48 mL | 12.41 mL | 24.83 mL |
5 mM | 0.5 mL | 2.48 mL | 4.97 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2