Rosiglitazone (BRL-49653)

Catalog No.: A10807

PPAR agonist

Rosiglitazone (BRL-49653)

Rosiglitazone (BRL-49653) Chemical Structure

CAS NO. 122320-73-4

Rosiglitazone works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin.

Availability: In stock

Package Price Qty
25 mg
$40.00
50 mg
$50.00
100 mg
$100.00
200 mg
$150.00
10mM * 1mL in DMSO
$50.00
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Biological Activity

Rosiglitazone works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin.
Targets
PPAR (Cell-free assay)
In vitro (25°C) DMSO 65 mg/mL (181.85 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.98 mL 139.9 mL 279.8 mL
0.5 mM 5.6 mL 27.98 mL 55.96 mL
1 mM 2.8 mL 13.99 mL 27.98 mL
5 mM 0.56 mL 2.8 mL 5.6 mL

*The above data is based on the productmolecular weight 357.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10807
Actions Agonist
CAS No. 122320-73-4
Formula C18H19N3O3S
M. Wt 357.4
Solubility DMSO
Purity >98%
Synonyms Avandia, BRL-49653
SMILES CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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