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Ruboxistaurin (LY333531)

PKC inhibitor

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Catalog No. A12399

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Ruboxistaurin (LY333531) 5mg A12399-5
Ruboxistaurin (LY333531) 10mg A12399-10
Ruboxistaurin (LY333531) 25mg A12399-25
Ruboxistaurin (LY333531) 100mg A12399-100

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Ruboxistaurin (LY333531) is a potent, selective inhibitor of Protein Kinase C isozymes, PKC β I(IC50=4.7 nM) and PKC β II (IC50=5.9 nM).

Ruboxistaurin (LY333531)

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Chemical Information

Catalog Num A12399
Actions Inhibitor
M. Wt 468.55
Formula C28H28N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 169939-94-0
Synonyms LY 333531, LY 333531
SMILES CN(C)C[[email protected]@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O

Biological Activity

Ruboxistaurin (LY333531) is a potent, selective inhibitor of Protein Kinase C isozymes, PKC β I(IC50=4.7 nM) and PKC β II (IC50=5.9 nM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.34 mL 106.71 mL 213.42mL
0.5 mM 4.27 mL 21.34 mL 42.68 mL
1 mM 2.13 mL 10.67 mL 21.34 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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