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Biological Activity
S(-)-Propranolol Hydrochloride is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol hydrochloride inhibits [3H]-DHA binding to rat brain membrane preparation with an IC50 of 12 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.81 mL | 169.03 mL | 338.07 mL |
| 0.5 mM | 6.76 mL | 33.81 mL | 67.61 mL |
| 1 mM | 3.38 mL | 16.9 mL | 33.81 mL |
| 5 mM | 0.68 mL | 3.38 mL | 6.76 mL |
*The above data is based on the productmolecular weight 295.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13428 |
|---|---|
| Actions | Blocker |
| CAS No. | CAS: 4199-10-4 |
| Formula | C16H22ClNO2 |
| M. Wt | 295.8 |
| Purity | >98% |
| Synonyms | S-(-)-PROPANOLOL HCL, (S)-PROPRANOLOL HYDROCHLORIDE |
| SMILES | CC(C)NC[[email protected]@H](COC1=CC=CC2=CC=CC=C21)O.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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