Saxagliptin (BMS-477118)

Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.
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Product Name Price Stock Qty
Saxagliptin 10mg
$90.00
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Saxagliptin 25mg
$150.00
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Saxagliptin 50mg
$240.00
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Saxagliptin 100mg
$350.00
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Saxagliptin (BMS-477118) 10mM * 1mL in DMSO
$91.00
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Adooq Products cited in reputable paper
Adooq's Saxagliptin (BMS-477118) has been cited by 5 publications
  • Ki-Young Kim, .et al. , Pharmaceutics, 2024, Jan 13;16(1):106 PMID: 38258116
  • OHE El-Shoubashy, .et al. , JPC, 2020, 33, 59-70
  • Sato T, .et al. , Sci Rep, 2019, Dec 2;9(1):18094 PMID: 31792328
  • Chintan N. Koyani, .et al. , Front Physiol, 2018, 9: 1622 PMID: 30487758
  • Koyani CN, .et al. , Biochem Pharmacol, 2016, Dec 1;145:64-80 PMID: 28859968
  • Biological Activity
    Discription Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.
    Targets
    Target Value
    Product Information
    Catalog Num A11109
    Formula C18H25N3O2
    Molecular Weight 315.4
    CAS Number 361442-04-8
    SMILES C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N
    Synonyms BMS-477118,Onglyza
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 62 mg/mL (196.57 mM)
    Water 62 mg/mL (196.57 mM)
    Ethanol 24 mg/mL (76.09 mM)
    In vivo Saline 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.71 mL 158.53 mL 317.06 mL
    0.5 mM 6.34 mL 31.71 mL 63.41 mL
    1 mM 3.17 mL 15.85 mL 31.71 mL
    5 mM 0.63 mL 3.17 mL 6.34 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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