Saxagliptin (BMS-477118)

Catalog No.: A11109

DPP-4 Inhibitor

Saxagliptin (BMS-477118)

Saxagliptin (BMS-477118) Chemical Structure

CAS NO. 361442-04-8

Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $90.00

Special Price $81.00

25 mg

Regular Price: $150.00

Special Price $135.00

50 mg

Regular Price: $240.00

Special Price $216.00

100 mg

Regular Price: $350.00

Special Price $315.00

10mM * 1mL in DMSO

Regular Price: $91.00

Special Price $81.90

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Saxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM.
Targets
DPP-4
26 nM
In vitro (25°C) DMSO 63 mg/mL (199.74 mM)
Water 63 mg/mL (199.74 mM)
Ethanol 24 mg/mL (76.09 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.71 mL 158.53 mL 317.06 mL
0.5 mM 6.34 mL 31.71 mL 63.41 mL
1 mM 3.17 mL 15.85 mL 31.71 mL
5 mM 0.63 mL 3.17 mL 6.34 mL

*The above data is based on the productmolecular weight 315.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11109
Actions Inhibitor
M. Wt 315.4
Formula C18H25N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 361442-04-8
Synonyms BMS-477118,Onglyza
SMILES C1[[email protected]@H]2C[[email protected]@H]2N([[email protected]@H]1C#N)C(=O)[[email protected]](C34CC5CC(C3)CC(C5)(C4)O)N

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