Signaling Pathway
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| Discription | SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM. | ||
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| Catalog Num | A11061 |
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| Formula | C16H10ClN3O5 |
| Molecular Weight | 359.7 |
| CAS Number | 264218-23-7 |
| SMILES | C1=CC=C(C(=C1)C2=C(C(=O)NC2=O)NC3=CC(=C(C=C3)O)Cl)[N+](=O)[O-] |
| Synonyms | SB-415286, SB415286 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 63 mg/mL (175.13 mM) | |
| Water | Insoluble | ||
| Ethanol | 63 mg/mL (175.13 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.8 mL | 139 mL | 278.01 mL |
| 0.5 mM | 5.56 mL | 27.8 mL | 55.6 mL |
| 1 mM | 2.78 mL | 13.9 mL | 27.8 mL |
| 5 mM | 0.56 mL | 2.78 mL | 5.56 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
